構成員

特別研究員 Cheng Tan

学歴

2007-2014 Ph.D. (physics) Nanjing University, China
2003-2007 B.Sc. (physics) Nanjing University, China

研究・教育歴

2019-present Postdoctoral researcher, RIKEN Center for Computational Science, Japan
2014-2019 Postdoctoral researcher, Kyoto University, Japan

所属学会

The biophysical society of Japan

研究テーマ

出版物

  1. Highly charged proteins and their repulsive interactions antagonize biomolecular condensation. Cheng Tan, Ai Niitsu and Yuji Suguita
    JACS Au 3, 834-848 (2023).
  2. Roe of water-bridged interactions in metal ion coupled protein allostery. Xingye Guan, Cheng Tan, Wenfei Li, Wei Wang and D Thirumalai
    PLOS Comput. Biol. 18, e1010195 (2022).
  3. Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations. Cheng Tan, Jaewoon Jung, Chigusa Kobayashi, Diego Ugarte La Torre, Shoji Takada and Yuji Suguita
    PLOS Comput. Biol. 18, e1009578 (2022).
  4. A singularity-free torsion angle potential for coarse-grained molecular dynamics simulations. Cheng Tan, Jaewoon Jung, Chigusa Kobayashi, and Yuji Suguita
    J. Chem. Phys. 153, 0441 (2020).
  5. Nucleosome allostery in pioneer transcription factor binding. Cheng Tan and Shoji Takada
    Proc. Natl. Acad. Sci. U.S.A 117, 20586-20596, (2020).
  6. New parallel computing algorithm of molecular dynamics for extremely huge scale biological systems. Jaewoon Jung, Chigusa Kobayashi, Kento Kasahara, Cheng Tan,  Akiyoshi Kuroda, Kazuo Minami, Shigeru Ishiduki, Tatsuo Nishiki, Hikaru Inoue, Yutaka Ishikawa, Michael Feig, and Yuji Sugita
    J. Comput. Chem. 42, 231-241 (2020)
  7. The HMGB chromatin protein Nhp6A can bypass obstacles when traveling on DNA. Kiyoto Kamagata, Kana Ouchi, Cheng Tan, Eriko Mano, Sridhar Mandali, Yining Wu, Shoji Takada, Satoshi Takahashi, and Reid C. Johnson.
    Nucleic Acids Res. 48(19) 10820-10831 (2020).
  8. Nucleosomes as allosteric scaffolds for genetic regulatio. Shoji Takada, Giovanni B. Brandani, and Cheng Tan
    J. Chem. Theory. Comput. , 14, 3877-3889 (2018).
  9. Dynamic and Structural Modeling of the Specificity in Protein–DNA Interactions Guided by Binding Assay and Structure Data. Cheng Tan and Shoji Takada
    Curr. Opin. Struct. Biol. 62 93-101 (2020).
  10. DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations. Giovanni B. Brandani, Toru Niina, Cheng Tan, and Shoji Takada
    Nucleic Acids Res. , 46, 2788-2801 (2018).
  11. Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations. Toru Niina, Giovanni B. Brandani, Cheng Tan, and Shoji Takada
    Plos Comput. Biol. , 13, e1005880 (2017).
  12. Dynamic Coupling among Protein Binding, Sliding, and DNA Bending Revealed by Molecular Dynamics. Cheng Tan, Tsuyoshi Terakawa, and Shoji Takada
    J. Am. Chem. Soc. , 138, 5812-5822 (2016).
  13. Modeling Structural Dynamics of Biomolecular Complexes by Coarse-Grained Molecular Simulations. Shoji Takada, Ryo Kanada, Cheng Tan, Tsuyoshi Terakawa, Wenfei Li, and Hiroo Kenzaki
    Acc. Chem. Res. , 48, 3026-3035 (2015).
  14. Atomistic picture for the folding pathway of a hybrid-1 type human telomeric DNA G-quadruplex. Yunqiang Bian, Cheng Tan, Jun Wang, Yuebiao Sheng, Jian Zhang, and Wei Wang
    Plos Comput. Biol. , 10, e1003562 (2014).
  15. Localized Frustration and Binding-Induced Conformational Change in Recognition of 5S RNA by TFIIIA Zinc Finger. Cheng Tan, Wenfei Li, and Wei Wang
    J. Phys. Chem. B , 117, 15917-15925 (2013a).
  16. Specific binding of a short miRNA sequence by zinc knuckles of Lin28: A molecular dynamics simulation study. Cheng Tan, Wenfei Li, and Wei Wang
    J. Theor. Comput. Chem. , 12, 1341015 (2013b).
  17. Low Folding Cooperativity of Hp35 Revealed by Single-Molecule Force Spectroscopy and Molecular Dynamics Simulation. Chunmei Lv, Cheng Tan, Meng Qin, Dawei Zou, Yi Cao, and Wei Wang
    Biophys. J. , 102, 1944-1951 (2013b).